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High-profile lab accidents last year with anthrax, Ebola and bird flu at the
"What the CDC incidents showed us ... is that the very best labs are not perfectly safe," says Marc Lipsitch, a Harvard University professor of epidemiology. "If it can happen there, it certainly can happen anywhere."
Some people find little reassurance that nobody was sickened in the CDC accidents or in the historically low numbers of serious infections among lab workers generally, or that infections spreading into communities surrounding labs have been rarer still.
"Many of us think that's really a matter of good fortune," said Beth Willis, who chairs a citizen lab advisory panel in Frederick, Md., home to one of the nation's largest high-containment research campuses at the Army's Fort Detrick .
The country's best labs have robust safety programs, said Kenneth Berns, co-chair of a panel of outside lab safety advisers currently examining biosafety at CDC and other federal labs. Yet the systemic safety problems identified at the CDC's prestigious labs have raised questions about what's happening elsewhere. "It's a matter of some concern," said Berns, a distinguished professor emeritus of molecular genetics and microbiology at the University of Florida .
The consequences could be devastating if accidents were to occur with lab-created strains of deadly influenza viruses that are purposely engineered to be easier to spread than what's found in nature, said David Relman, a microbiology professor at Stanford University who is a federal adviser on lab safety and a past president of the Infectious Diseases Society of America .
"You're talking about something that has the ability to take off, and we could not be confident of being able to contain it," he said.
Relman said that not enough is known about the state of safety at labs that perform infectious disease research but emphasized that the kinds of labs drawing concern are the same ones the public needs to discover important new treatments and vaccines. "We have to find some happy blend of minimized risk and enhanced benefit," he said.
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